Mitochondrial Eve?!

Whilst doing some research for my dissertation piece, I stumbled upon a very interesting topic about a woman; mitochondrial Eve.
According to the experts in human evolutionary genetics, Mitochondrial eve is the matrilineal, most recent common ancestor of modern humans! To you and me, this simply means that Mitochondrial Eve is our great, great, great, greatest, even greater than that, grandmother.

So how did the experts figure this out? Mitochondrial DNA is passed from mother to offspring without recombination, so therefore, all mitochondrial DNA in every living person is exactly identical to their mother's, and her mother's mother, and so on. So therefore we can use mitochondrial DNA to trace back the earliest of modern humans. Mitochondrial Eve is estimated to have lived around 160,000 to 200,000 years ago, in East Africa. Unlike the Biblical Eve, Mitochondrial eve was not the first and only woman alive during her time, however, her offspring are the only ones who made it into modern humanity, meaning the offspring of the other women of her time died off at some point. e.g. by only having male offspring that could not pass on the genetic information, or by dying through natural causes before reproducing. Times were tough back then. (I imagine). It was the discovery of mitochondrial Eve that made the hypothesis that modern humans originated recently from Africa and then spread from Africa to the rest of the world, replacing the archaic human populations that existed at the time, such as the neanderthals, the predominant and leading theory supporting our origin.

Y - Chromosomal AdamMitochondrial Eve is not our only most recent common ancestor! Meet Y-Chromosomal Adam. The Y chromosome is another part of the genome that is not shuffled about by evolutionary mechanisms in order to generate diversity. This means that the male Y chromosome is passed on in tact, so therefore Y chromosomal Adam is our great, great, most greatest, even greater than that grandfather. Y-chromosomal Adam is estimated to have lived also in Africa but at a different time to Eve, 140,000 years ago. Using mitochondrial DNA analysis we can look back on the genetic ancestry of the modern human like never before.

In my next post, I will be explaining the four main thoeries which try to explain the origin of the modern human.

Journal Review: Why did modern human populations disperse from Africa 60,000 years ago?

This post is based on a very enlightening paper I came across in the Joural "Proceedings of the National Academy of Sciences", written by Paul Mellars in 2006.

The paper 'Why did modern human populations disperse from Africa 60,000 years ago? helped to confirm the current beliefs on the origins of the modern human. Modern humans, are those who are anatomically and genetically identical to humans today and research shows that these modern humans emerged from Africa up to 200,000 years ago.

However, around 65,000 B.P (before present), a major dispersal towards Asia and Europe occured. Research in this department tends to use genetic methods, using mitochondrial DNA (mtDNA) analysis and comparison, matched with archeological findings. These findiNgs suggest a sudden increase in the complexicity of technological, economic, social and cognitive behaviour of certain African groups which could have led to their demographic expansion due to competition with one another.The paper further suggests that it is the development of advanced behavioural changes that could have led to the expansion of the L2 and L3 mitochondrial lineages over Africa, to Asia and Europe. The behavioural changes may have also helped these modern humans to replace the 'archaic' humans that previously occupied these regions, with or without interbreeding.

The paper shows what the science community now knows about the mdoern human...DNA patterning of present world populations and archeological findings of skeletal remains shows that populations that were genetically and anatomically 'modern' emerged from Africa up to 50,000 years ago. These populationas dispersed from Africa to other parts of the world around 40,000n years ago, where they replaced the pre-existing 'archaic' populations there, such as the European Neanderthals.

The paper raises the question of why it took the modern human up to 100,000 years to disperse from Africa, and what are the crucial evolutionary and adaptive developmets tahta allowed these populations to colonise and defeat a range of entirely different environemts and its inhabitants. The paper further suggests that the answer to these questions lies partly in the results of recent DNA analysis among different geographical groups of Africans of the present day.
In my next post, I will be looking further into key discoveries that have been made over the past 2 decades that helped form our current understanding of where we came from.